What causes kidney damage from L-carnitine?
Disease description:
Recently trying to lose weight, a friend suggested taking L-carnitine, but I heard it may harm the kidneys. May I ask what causes L-carnitine to damage the kidneys?
Doctor's answer (1)
Dr. Yang Ziqi
L-carnitine may affect kidney health primarily due to the following factors:
1. Metabolic burden: During its metabolism in the body, the kidneys are involved in excreting L-carnitine's metabolic byproducts. Long-term, high-dose use increases the excretory burden on the kidneys, particularly in individuals with existing kidney problems or underlying medical conditions.
2. Functional impact: Excessive long-term intake of L-carnitine may reduce the glomerular filtration rate and increase the workload on the renal tubules, thereby negatively affecting kidney function and potentially leading to kidney damage.
3. Interactions: The use of L-carnitine may interact with other medications or health factors, further increasing the risk of kidney injury.
L-carnitine should be used under medical supervision to avoid excessive intake.
