The Risks of Orlistat for Weight Loss

Jul 12, 2024 Source: Cainiu Health
Disease description:

Male, 28 years old: I have been staying at home for a long time, consistently eating takeout food without exercising, and now I weigh over 300 pounds. I previously visited the hospital and was prescribed Orlistat. May I ask what are the potential risks or side effects associated with using Orlistat for weight loss?

Doctor's answer (1)
Dr. Yang Ziqi
Orlistat is an over-the-counter weight-loss medication. Its main ingredient, orlistat, works by inhibiting intestinal lipase, thereby reducing the absorption of dietary fat and helping to reduce body weight. There may be some potential risks and side effects associated with the use of orlistat: 1. **Fatty diarrhea**: Because the drug blocks fat absorption, unabsorbed fat may lead to oily stools and accidental oil discharge, which can cause abdominal discomfort, diarrhea, and urgent bowel movements. 2. **Gallbladder problems**: Although rare, orlistat may increase the risk of gallbladder disease, especially in individuals who already have gallbladder issues. 3. **Heart problems**: Although study results have been mixed, some reports suggest that orlistat might be associated with an increased risk of cardiovascular events and should be monitored. 4. **Other side effects**: These may include headache, stomach pain, flu-like symptoms, joint pain, and menstrual irregularities. **Note**: When using orlistat for weight loss, you should follow medical advice. If serious side effects occur, seek medical attention promptly.