Causes of Elevated Indirect Bilirubin
Disease description:
When I had my liver checked, the results showed that my indirect bilirubin level was elevated. I would like to ask the doctor, what are the possible causes of elevated indirect bilirubin?
Doctor's answer (1)
Dr. Liu Feng
The main causes of elevated indirect bilirubin levels are as follows:
1. Liver diseases: Such as hepatitis and cirrhosis. These conditions can impair liver function, affecting the normal conversion and excretion of bilirubin, thereby leading to elevated levels of indirect bilirubin.
2. Hemolytic anemia: When a large number of red blood cells are destroyed in the body, excessive indirect bilirubin is released, exceeding the liver's capacity for conversion. This causes indirect bilirubin to remain in the bloodstream for prolonged periods, resulting in elevated levels.
3. Blood transfusion with incompatible blood types: Transfusion of incompatible blood can easily trigger a hemolytic reaction, leading to red blood cell destruction and subsequently elevated indirect bilirubin levels.
4. Non-disease factors: Such as long-term high-fat and high-sugar diets, excessive alcohol consumption, medication effects (e.g., long-term use of isoniazid, methyldopa, and other drugs), and obesity.
