What does alanine aminotransferase (ALT) mean?

Jul 13, 2024 Source: Cainiu Health
Disease description:

I have a history of hepatitis. During the examination, the doctor mentioned alanine aminotransferase (ALT). I would like to ask, what does alanine aminotransferase mean?

Doctor's answer (1)
Dr. Yang Ziqi

Alanine aminotransferase (ALT) is an enzyme primarily found in liver cells, although it also exists in the heart, muscles, and other tissues. Its main function is to assist in the conversion of amino acids during amino acid metabolism. When liver cells are damaged or destroyed, ALT is released into the bloodstream. Therefore, the level of ALT in the blood can serve as an indicator for assessing liver health.

If the level of ALT in the blood increases, it usually indicates damage to liver cells, which may be caused by hepatitis, fatty liver disease, cirrhosis, excessive alcohol consumption, certain medications, or toxins. However, high ALT levels do not necessarily mean serious liver disease; they may also result from other non-liver-related factors. Doctors typically evaluate the exact cause by combining other liver function tests and clinical symptoms.

In daily life, maintaining a healthy diet, engaging in appropriate physical activity, avoiding excessive alcohol consumption, and undergoing regular medical checkups can help maintain normal liver function. If test results show elevated ALT levels, prompt medical attention is recommended.