What causes elevated transaminase levels?
Disease description:
During a liver examination, they mentioned that my transaminase levels were high. I would like to ask, what are the causes of elevated transaminase levels?
Doctor's answer (1)
Dr. Yang Ziqi
Elevated transaminases usually refer to increased levels of alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) in the blood, which may be caused by various factors:
1. Liver diseases: Common causes include hepatitis (such as viral hepatitis—types A, B, C, etc.), fatty liver disease, alcoholic liver disease, and autoimmune liver diseases. These conditions can damage liver cells, causing transaminases to be released into the bloodstream.
2. Alcohol abuse and medications: Long-term heavy alcohol consumption and certain drugs (e.g., acetaminophen, some antibiotics, anticancer medications, etc.) can lead to liver injury, resulting in elevated transaminase levels.
3. Other organ disorders: Although less common, heart or kidney disease, pancreatitis, or muscle injuries may also affect transaminase levels.
4. Other factors: Vigorous exercise, obesity, malnutrition, genetic disorders, cirrhosis, liver cancer, pregnancy, or stressful conditions may also cause temporary increases in transaminase levels.
If elevated transaminases are detected, it is recommended to seek medical attention promptly.
