What are the chemotherapy drugs for colon cancer?
Disease description:
I am a colorectal cancer patient myself, and I need to undergo chemotherapy. I would like to know, what are the chemotherapy drugs used for colorectal cancer?
Doctor's answer (1)
Dr. Shen Yonghua
The main chemotherapy drugs for colorectal cancer include the following:
1. Fluorouracil (5-FU): This is a cell cycle-specific drug that acts during the S-phase, stopping tumor cell proliferation and inhibiting replication.
2. Calcium Folinate (CF): Often used in combination with fluorouracil, it enhances the biological activity of fluorouracil.
3. Oxaliplatin (L-OHP): This drug can inhibit DNA replication and transcription in tumor cells, thereby exerting an antitumor effect.
4. Irinotecan (CPT-11): A camptothecin-derived anticancer drug, it is widely used clinically due to its strong anticancer activity and relatively low toxicity.
5. Topotecan (TPT): Also a camptothecin-derived anticancer drug, it demonstrates significant antitumor efficacy.
The use of the above medications must strictly follow medical instructions and should be adjusted according to the patient's specific condition.
