Which one is better for blood pressure reduction, Plendil or extended-release nifedipine tablets?

Both Plendil (extended-release felodipine) and Adalat CC (extended-release nifedipine) demonstrate good antihypertensive effects. Both medications belong to the class of calcium channel blockers, although their specific mechanisms of action differ slightly. Plendil lowers blood pressure by inhibiting calcium ion influx into cells, whereas Adalat CC reduces peripheral vascular resistance through vasodilation, thereby lowering blood pressure. Regarding the comparison of antihypertensive efficacy, neither medication is absolutely superior to the other, and individual responses may vary due to patient-specific differences. Adalat CC, as a long-acting antihypertensive agent, maintains stable drug concentrations over a 24-hour period and may be more suitable for patients requiring consistent blood pressure control. Plendil also offers unique advantages, such as cardiovascular protection and improvement of insulin resistance. Therefore, when selecting an antihypertensive medication, comprehensive consideration should be given to the patient's specific medical condition, age, gender, comorbidities, and other relevant factors, with appropriate drug selection made under a physician's guidance. Additionally, regardless of the chosen medication, it is essential to follow medical instructions precisely regarding dosage and timing, monitor blood pressure changes regularly, and adjust the treatment regimen accordingly.