Eosinophil Count Elevation Causes

Eosinophilia, medically referred to as an elevated eosinophil count, may be caused by the following reasons: 1. **Allergy**: Allergic reactions are one of the causes of elevated eosinophils. Stimulation by allergens leads to increased secretion of interleukins from cells, which activates the production of specific IgE, resulting in elevated eosinophil levels. 2. **Hematologic diseases**: Abnormal proliferation of leukocytes in peripheral blood and bone marrow can lead to a high number of eosinophils in the bloodstream. 3. **Malignant tumors**: Many malignant tumors, such as lung cancer, may cause eosinophils to migrate and engulf related pathogens when lymph nodes are involved. During this process, the number of eosinophils increases. 4. **Infectious diseases**: Most infectious diseases cause increased white blood cell production, which may elevate eosinophil levels. However, in most cases, eosinophil counts return to normal during the recovery phase. Only in patients with scarlet fever does tissue inflammation occur during recovery, and the bacterial capsule produced resists phagocytosis by eosinophils, causing eosinophil counts to remain elevated. 5. **Parasitic infections**: Parasitic infection is the most common cause of elevated eosinophil count. Diseases such as ascariasis, schistosomiasis, filariasis, and hookworm disease can trigger an immune response upon parasite invasion, leading to an increase in eosinophils. 6. **Skin diseases**: The skin serves as an external defense organ. Skin conditions such as acne, eczema, dermatitis, and tinea can cause symptoms such as redness, itching, and papules, which may lead to elevated eosinophil levels.