Will closed comedones go away on their own?

Whether closed comedones resolve on their own depends on their severity and individual circumstances. If the number of closed comedones is small and symptoms are mild, they may resolve spontaneously. This is because the body's immune system can suppress local inflammatory factors, promoting gradual resolution of the comedones. However, this process may be relatively slow, and patients should maintain skin cleanliness, avoiding excessive scrubbing or manually picking at the comedones to prevent infection. If the closed comedones are numerous or symptoms are severe—for example, if they are明显 protruding from the skin surface and accompanied by redness, swelling, and pain—they generally will not resolve on their own. In such cases, patients are advised to seek timely medical attention and use appropriate medications under a physician's guidance, such as tretinoin cream or adapalene gel. If pharmacological treatment proves ineffective, aesthetic medical treatments such as chemical peels or laser therapy may also be considered.