Why does systemic lupus erythematosus recur repeatedly?

Jul 19, 2024 Source: Cainiu Health
Disease description:

I was diagnosed with systemic lupus erythematosus (SLE) not long ago, and it has been recurring frequently recently. May I ask why systemic lupus erythematosus tends to recur repeatedly?

Doctor's answer (1)
Dr. Yang Tiesheng
The main reasons for the recurrence of systemic lupus erythematosus include the following: 1. Infection: This is one of the most common triggers, including infections of the respiratory tract, gastrointestinal tract, and other areas, caused by pathogens such as Staphylococcus aureus. 2. Medication factors: Patients reducing or discontinuing medication on their own, or using certain drugs such as penicillamine and chlorpromazine, may induce relapse. 3. Pregnancy: Female patients have a higher recurrence rate during pregnancy, which is related to disease activity and severity. 4. Emotional stress and fatigue: Emotional fluctuations and excessive fatigue are also factors that can trigger disease recurrence. 5. Inadequate immunomodulatory therapy: Insufficient immunomodulatory treatment may lead to immune dysfunction, which can trigger relapse. If you have any concerns, it is recommended to seek medical attention promptly.