Is being a "big three positive" contagious?
Disease description:
I have a male colleague who is 33 years old. He was diagnosed with "Big Three Yang" (positive for HBsAg, HBeAg, and anti-HBc) one week ago. We usually have a good relationship and often eat together. I'm concerned about whether "Big Three Yang" is contagious.
Doctor's answer (1)
Dr. Yang Ziqi
The "big three positives" are contagious.
"Big three positives" is a clinical manifestation of chronic hepatitis B, specifically referring to the presence of three markers in the patient's blood: hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), and hepatitis B core antibody IgM (anti-HBc IgM). This indicates active viral replication in the body and a higher level of contagiousness.
Transmission mainly occurs through blood, mother-to-child vertical transmission, and sexual contact. In daily life, behaviors such as sharing toothbrushes or razors that may lead to blood contact can also result in the spread of the hepatitis B virus.
For individuals with the "big three positives" and their close contacts, necessary preventive measures should be taken, regular medical monitoring performed, and standardized treatment carried out under the guidance of a qualified physician, in order to control disease progression and reduce transmission risks.
To prevent hepatitis B infection, it is recommended to receive the hepatitis B vaccine and avoid sharing items that may come into contact with blood with individuals who have hepatitis B. At the same time, patients with hepatitis B should also actively undergo treatment to reduce viral load and decrease contagiousness.
