What diseases are commonly associated with red blood cell casts in urine?

Aug 12, 2024 Source: Cainiu Health
Disease description:

I would like to ask the doctor, is the presence of red blood cell casts in the urine a symptom commonly seen in which diseases?

Doctor's answer (1)
Dr. Cao Zhiqiang

Common diseases associated with red blood cell casts in urine include the following:

1. Acute glomerulonephritis: Acute onset, commonly seen after streptococcal infection; urinalysis reveals numerous red blood cells and red blood cell casts.

2. Chronic glomerulonephritis: The disease progresses slowly; persistent presence of red blood cell casts suggests chronic kidney damage.

3. Tubular diseases: Certain tubular disorders, such as acute tubular necrosis, may also lead to the presence of red blood cell casts. Besides acute tubular necrosis, other tubulointerstitial diseases, such as drug-induced nephropathy, may also result in red blood cell casts.

4. Autoimmune diseases such as lupus nephritis: When diseases like systemic lupus erythematosus affect the kidneys, urinalysis may reveal red blood cell casts.

5. Non-disease factors: Urine contamination can also lead to the presence of red blood cell casts, for example, menstrual blood contamination in women during menstruation. Therefore, when red blood cell casts are detected, the possibility of urine contamination should be ruled out.