What are the side effects of Metformin and Vildagliptin Tablets?

Aug 13, 2024 Source: Cainiu Health
Disease description:

I am a diabetic patient who has been taking Metformin and Vildagliptin tablets. I heard from a friend that this medication has quite a few side effects. Could you please tell me what the side effects of this drug are?

Doctor's answer (1)
Dr. Liu Feng

Metformin and vildagliptin tablets, as a commonly used drug combination in the treatment of type 2 diabetes, mainly contain two components: metformin and vildagliptin. These two medications lower blood glucose levels through different mechanisms. Metformin primarily reduces glucose production in the liver and increases the body's sensitivity to insulin, while vildagliptin increases insulin secretion and reduces glucagon secretion by inhibiting the DPP-4 enzyme. The main side effects include:

1. Gastrointestinal reactions: Common symptoms include nausea, vomiting, bloating, and diarrhea.

2. Nervous system reactions: May cause headache, dizziness, tremors, etc.

3. Hypoglycemic reactions: May lead to symptoms such as dizziness, headache, drowsiness, weakness, trembling, and rapid heartbeat.

4. Allergic reactions: Such as rash, urticaria, itching, etc. Severe cases may experience symptoms like difficulty breathing, swallowing, or speaking.

It is recommended to use this medication under a doctor's guidance. If any discomfort occurs, seek medical attention promptly.