Is a creatine kinase level of 547 serious?

Aug 13, 2024 Source: Cainiu Health
Disease description:

Doctor, today I went to the hospital for a physical examination and found that my creatine kinase level is 547. May I ask, is this serious?

Doctor's answer (1)
Dr. Tian Hongbo

The creatine kinase (CK) level of 547 U/L is higher than the normal range. Creatine kinase is a muscle enzyme that is released into the bloodstream when muscles or the heart are damaged. Normally, the reference range for creatine kinase in males is 50 U/L to 310 U/L, and for females, it is 40 U/L to 200 U/L. Reference values may vary slightly between different laboratories. A creatine kinase level of 547 U/L is significantly above the normal range, which may indicate the presence of muscle damage or disease.

Elevated creatine kinase levels can be caused by various factors, including strenuous exercise, medication effects, hypothyroidism, fractures, muscle injury, rhabdomyolysis, myocarditis, myocardial infarction, tumors, and inflammatory infections. Whether the specific creatine kinase value is serious needs to be determined based on clinical symptoms and other test results.

If the patient has recently engaged in strenuous physical activity, the elevated CK level may be temporary; however, if CK levels remain elevated without significant muscle activity, it may suggest myocardial infarction, myositis, muscular disorders, or other serious conditions, and timely medical consultation is recommended.