How long can someone live with Henoch-Schönlein purpura nephritis?

Sep 25, 2024 Source: Cainiu Health
Disease description:

I've been stumbling and falling frequently lately, resulting in many purple bruises. Sometimes my kidneys also feel uncomfortable. The doctor diagnosed me with Henoch-Schönlein purpura nephritis. I'd like to know, how long can someone live with this condition?

Doctor's answer (1)
Dr. Yang Guang

IgA vasculitis (Henoch-Schönlein purpura) nephritis is a kidney disease caused by hypersensitivity vasculitis, mainly manifested as skin purpura, joint pain, abdominal pain, and kidney damage.

In general, most patients with IgA vasculitis nephritis can achieve effective control of the disease, and even clinical cure, after active treatment. Their life expectancy is similar to that of the general population, and they can survive for a long time. However, some patients may develop complications such as renal insufficiency and uremia, which may shorten survival time. These patients may live for 10–20 years, or even less.

For patients with mild to moderate IgA vasculitis nephritis, timely and effective treatment can often lead to clinical remission or even complete recovery. Their quality of life may remain similar to that of healthy individuals, and their life expectancy is generally not significantly affected. Treatment may include glucocorticoids, immunosuppressive agents, and symptomatic and supportive therapies. For patients with severe IgA vasculitis nephritis, especially those who develop acute kidney injury or chronic renal failure, the prognosis may be poor. These patients may require long-term dialysis treatment or even kidney transplantation.