How to lower high bilirubin levels in pregnant women

Elevated bilirubin levels in pregnant women, especially increased direct bilirubin, may indicate intrahepatic cholestasis of pregnancy or other liver diseases. Intrahepatic cholestasis of pregnancy is a specific complication of pregnancy, mainly characterized by elevated serum total bile acid and bilirubin levels, accompanied by pruritus. The management principles are as follows:

1. Dietary adjustment: Pregnant women are advised to follow a light and balanced diet, ensuring adequate caloric intake, protein, and vitamins. High-quality, high-protein foods such as fish, eggs, and milk can be consumed. Additionally, sufficient water intake is recommended to replenish bodily fluids, improve circulation, and promote metabolism.

2. Lifestyle management: Pregnant women should maintain healthy lifestyle habits, avoid excessive fatigue and staying up late, and ensure adequate rest.

3. Pharmacological treatment: Ursodeoxycholic acid is the first-line treatment for intrahepatic cholestasis of pregnancy. It effectively reduces serum bile acid levels and improves maternal and fetal outcomes. Antihistamines or short-term corticosteroids may be added for severe pruritus.

4. Surgical treatment: If a pregnant woman is diagnosed with elevated bilirubin caused by gallstones and conservative treatment is ineffective or serious complications arise, surgical intervention such as laparoscopic cholecystectomy may be required.