Human Chorionic Gonadotropin Range

Human chorionic gonadotropin, or hCG, is a glycoprotein hormone secreted by placental trophoblast cells. Its normal range varies greatly among different populations and under different physiological conditions. In non-pregnant women, serum hCG levels are typically below 5 mIU/mL. However, during pregnancy, hCG levels rise significantly, doubling approximately every two days until reaching a peak at 8–10 weeks of gestation, after which they gradually decline.

Specifically, in early pregnancy, hCG levels increase rapidly. At 3 weeks of gestation, hCG may be below 50 IU/L, and below 400 IU/L at 4 weeks. From the middle to late stages of pregnancy, hCG continues to rise, reaching 5,000–90,000 IU/L at 7 weeks gestation, and peaking at 40,000–230,000 IU/L around 10 weeks of pregnancy. Subsequently, levels gradually decline to lower concentrations at term, being approximately 8,000–100,000 IU/L at 6 months of gestation and decreasing to 5,000–65,000 IU/L at 9 months of pregnancy.