What should not be taken with folic acid
Disease description:
After getting married, I have been taking folic acid tablets during this period because we are actively preparing for pregnancy and hoping to have a baby. However, I would still like to ask: what should not be taken together with folic acid?
Doctor's answer (1)
Dr. Yang Ziqi
In terms of food, folic acid is relatively stable in alkaline and neutral environments but is easily destroyed in acidic conditions. Therefore, it should not be consumed simultaneously with foods rich in vitamin C or those that create an acidic environment in the body, such as oranges, carrots, tomatoes, and vinegar. In addition, spicy and irritating foods like chili peppers and hot pot may also affect the absorption of folic acid and could potentially cause indigestion.
Folic acid should not be taken with certain medications. Anticonvulsants such as phenytoin and phenobarbital may reduce the bioavailability of folic acid, thereby affecting its efficacy. Furthermore, oral contraceptives may interfere with folic acid metabolism, leading to decreased levels. Therefore, patients taking these medications should consult a physician before supplementing with folic acid to adjust the dosage or monitor serum folate levels.
Alcohol consumption can affect the metabolism and absorption of folic acid. Long-term heavy drinking may lead to folic acid deficiency, as alcohol increases the excretion of folic acid and interferes with its storage and utilization in the liver. Therefore, to maximize the health benefits of folic acid, alcohol intake should be limited.
