Does hyaluronic acid injection require refrigeration?

Hydrofillers typically need to be refrigerated during storage.

Hydrofillers contain various nutritional components such as hyaluronic acid and collagen, which can easily degrade in high temperatures, thus affecting the treatment effectiveness. Refrigeration can slow down the degradation of these components and maintain the quality of the hydrofiller. Additionally, refrigeration reduces the risk of microbial contamination and extends the shelf life of the hydrofiller. It is generally recommended to store hydrofillers at a refrigerated temperature between 2°C and 8°C. Once a hydrofiller is opened and ready for use, refrigeration is no longer necessary during the injection process.

Prior to use, the hydrofiller should be removed from the refrigerator and allowed to reach room temperature before injection to avoid causing local discomfort. After opening, hydrofillers should be used promptly and not left exposed to air for extended periods to prevent bacterial contamination. Before using a hydrofiller, it is also important to check for any signs of deterioration, such as discoloration or unusual odor, to ensure safety. It is advisable to have hydrofiller injections administered at professional medical facilities to ensure the safety and effectiveness of the procedure.