How long does it take for hyaluronic acid dissolution to take effect?

Feb 17, 2025 Source: Cainiu Health
Disease description:

After receiving hyaluronic acid injections, I am not satisfied with the filling results and would like to receive hyaluronidase injections to dissolve the hyaluronic acid. I would like to know how long it takes for hyaluronidase to take effect in dissolving hyaluronic acid.

Doctor's answer (1)
Dr. Chen Lu

In general, the effect of dissolving hyaluronic acid can be observed 7 to 10 days after the injection of the dissolving enzyme.

Hyaluronic acid is a filler widely used in aesthetic medicine that can add volume to the skin, reduce wrinkles, and enhance facial contours. The effects of hyaluronic acid fillers typically last from 6 months to 1 year, depending on the individual's metabolic rate, lifestyle, and the brand and type of filler used. Over time, the hyaluronic acid will be naturally absorbed by the body, and its effects will gradually diminish until they disappear completely.

Individuals with a faster metabolism may see results in about 7 days, while those with a slower metabolism might require up to 10 days. Additionally, the dosage and injection site of the hyaluronic acid can affect the dissolution time. If a larger dose was injected or the injection site is more complex, the dissolution process may take longer.

To ensure safety and optimal results, it is recommended to undergo the hyaluronic acid dissolution procedure under the guidance of a qualified physician. Furthermore, patients should follow their doctor's instructions after treatment and avoid massaging or rubbing the injection area to prevent unnecessary complications. After dissolving hyaluronic acid, patients may experience mild swelling, redness, or pain at the injection site, which typically resolves on its own within a few days. If any unusual symptoms or persistent discomfort occur, patients should promptly contact their doctor for evaluation and appropriate management.