
Which is more expensive, hyaluronic acid with a large molecular weight or small molecular weight?
I have recently been considering facial fillers using hyaluronic acid, and I learned that hyaluronic acid comes in different molecular sizes—high molecular weight and low molecular weight. It seems their prices also vary. Could you please tell me, doctor, which type—high molecular weight or low molecular weight hyaluronic acid—is more expensive?

In general, due to its higher water-retention capacity and more complex production process, high molecular weight hyaluronic acid may cost more than low molecular weight hyaluronic acid.
Hyaluronic acid, a commonly used material for cosmetic fillers, can be categorized into high molecular weight, medium molecular weight, and low molecular weight based on its molecular size. Different molecular weight hyaluronic acids have various applications in aesthetic medicine—for example, high molecular weight hyaluronic acid, with its firmer consistency, is more suitable for shaping procedures such as nasal bridge or chin augmentation, while low molecular weight hyaluronic acid is primarily used to improve skin condition, such as hydration and moisturizing.
When selecting a hyaluronic acid product, personal skin needs should be considered first. If the skin is dry and dehydrated, high molecular weight hyaluronic acid products may be chosen for deep hydration; if fine lines or wrinkles are the primary concern, low molecular weight hyaluronic acid may be more appropriate. Additionally, it is recommended to consult with a qualified dermatologist or aesthetic specialist to select the most suitable hyaluronic acid product based on individual skin condition and aesthetic goals. When purchasing, ensure to choose reputable channels and well-known brands to guarantee product quality and safety. Also, considering budgetary factors, comparing prices of different brands and specifications can help identify a cost-effective option.