Can infants consume formula containing lactoferrin on a long-term basis?

Babies generally should not consume formula containing lactoferrin for a prolonged period. Lactoferrin is an important nonspecific defense factor that has multiple physiological functions, including enhancing immunity and promoting iron absorption. Appropriate intake is beneficial for infants. However, long-term and excessive consumption of formula containing lactoferrin may cause some adverse effects. On one hand, lactoferrin can inhibit the growth of intestinal bacteria, potentially disrupting the balance of the intestinal microbiota, affecting gastrointestinal function, causing malabsorption, and leading to symptoms such as diarrhea and green-colored stools in babies. On the other hand, lactoferrin is metabolized through bile and its metabolites are excreted via the kidneys; therefore, long-term excessive intake may increase the burden on the liver and kidneys. In addition, long-term dependence on lactoferrin may reduce a baby's interest in other foods, resulting in an unbalanced nutrient intake.

Therefore, when selecting formula for their baby, parents should choose an appropriate brand and type based on the baby's constitution and nutritional needs. If a baby needs supplemental lactoferrin, it should be done under a doctor's guidance with proper dosage, and parents should closely monitor the baby's response and physical condition. Furthermore, as the baby grows older, complementary foods should be introduced in a timely manner to ensure comprehensive and balanced nutrition.