Is it dangerous to infuse intravenous fluid into the subcutaneous tissue?

Mar 21, 2025 Source: Cainiu Health
Disease description:

During the intravenous infusion, I noticed that the medication had leaked into the subcutaneous tissue, and my hand became swollen. I felt very anxious and would like to ask the doctor: is there any danger if an intravenous infusion infiltrates into the subcutaneous tissue?

Doctor's answer (1)
Dr. Liu Feng

In general, there is a certain degree of risk associated with extravasation of intravenous (IV) fluids into subcutaneous tissue.

IV infusion is a common medical treatment used to replenish fluids, electrolytes, or medications. Normally, IV fluids are administered through a vein to ensure that the medication or fluid rapidly enters the circulatory system and exerts its intended effects. However, due to improper technique or equipment malfunction, IV fluids may sometimes be unintentionally infused into the surrounding subcutaneous tissue, a condition known as extravasation. Some medications are irritating or toxic to tissues and may cause local tissue damage, pain, swelling, necrosis, or even infection.

Strict adherence to proper procedures during IV infusion is essential to ensure the needle is accurately inserted into the vein. If extravasation occurs due to poor venous conditions, dislodgement of the needle, or patient non-cooperation, it should be promptly identified and the infusion site adjusted to prevent adverse outcomes.

During IV infusion, healthcare providers should closely monitor the patient's response to ensure infusion safety. At the same time, patients should actively cooperate with medical staff, keep the infusion site stable, and avoid moving the area unnecessarily, which may lead to needle dislodgement or incorrect infusion placement.