Can omeprazole pellets be used for a long time?

May 20, 2025 Source: Cainiu Health
Disease description:

I have been taking omeprazole pellets for some time, and my symptoms have improved significantly. I would like to ask if this medication can be taken long-term, and whether there might be any side effects.

Doctor's answer (1)
Dr. Shen Yonghua

Omeprazole pellets are generally not intended for long-term use, and it's important to use them appropriately under the guidance of a physician.

Omeprazole belongs to a class of medications called proton pump inhibitors, primarily used to treat conditions caused by excessive stomach acid, such as gastric ulcers and duodenal ulcers. Short-term use effectively controls symptoms, but long-term usage requires caution. Prolonged administration may increase the risk of osteoporosis, infections, interfere with drug metabolism, and potentially cause magnesium deficiency.

In addition, it may cause gastrointestinal adverse reactions such as nausea and abdominal distension. It may also lead to neurological abnormalities such as dizziness and headaches. Furthermore, it could result in abnormal calcium absorption.

Patients should use this medication under the guidance of a doctor, with regular evaluation of its effectiveness and side effects, avoiding long-term self-medication without medical advice. The principle of "rational drug use" should always be followed for any medication, aiming to achieve optimal therapeutic effects with minimal side effects. A proper diet should also be maintained during treatment, avoiding spicy and irritating foods such as hot pot and chili peppers, which may interfere with the drug's effectiveness.