What medication should be taken for mild gastric ulcers?

May 23, 2025 Source: Cainiu Health
Disease description:

During a recent physical examination, I was found to have a mild gastric ulcer. I occasionally experience stomach bloating and mild pain, particularly when fasting. What medications would be suitable for me? Is it necessary to use acid-suppressing drugs or gastric mucosal protectants?

Doctor's answer (1)
Dr. Shen Yonghua

The treatment of mild gastric ulcers typically requires a combination of medication and lifestyle adjustments.

Proton pump inhibitors (PPIs), such as omeprazole and lansoprazole, reduce gastric acid secretion by inhibiting the proton pump activity of gastric wall cells, thereby alleviating symptoms of gastric ulcers. These medications are usually taken orally and are more effective when taken on an empty stomach before meals.

H2 receptor antagonists, such as ranitidine and famotidine, block H2 receptors on gastric wall cells, thereby reducing gastric acid secretion. These medications are also primarily administered orally. Gastric mucosal protectants, such as colloidal bismuth pectin and sucralfate, form a protective layer over the ulcer site, promoting healing.

If the ulcer is caused by Helicobacter pylori, a combination of antibiotics, such as clarithromycin and amoxicillin, should be used together with PPIs and gastric mucosal protectants as part of an eradication regimen. Gastric motility promoters, such as domperidone tablets and mosapride citrate tablets, enhance gastrointestinal motility and improve digestive function, thereby relieving symptoms such as bloating and nausea.

Medications should be selected and used under the guidance of a qualified physician. Additionally, attention should be given to dietary regulation, avoiding spicy and greasy foods, and maintaining a regular作息 schedule.