Can pregnant women take ibuprofen?

Generally, pregnant women are not advised to take ibuprofen casually to avoid potential adverse effects.

Ibuprofen belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the activity of cyclooxygenase, thereby reducing the synthesis of prostaglandins. This results in reduced inflammatory response and pain perception, providing antipyretic, analgesic, and anti-inflammatory effects.

During the early stages of pregnancy, when fetal organs are undergoing differentiation and development, ibuprofen may interfere with embryonic growth and increase the risk of developmental abnormalities in the fetus's heart, kidneys, and other organs. Taking ibuprofen during late pregnancy can inhibit prostaglandin synthesis, potentially causing premature closure of the fetal ductus arteriosus, leading to pulmonary hypertension, and may also impair uterine contractions, increasing the risk of postpartum hemorrhage in the mother. Ibuprofen should be used only in cases of severe maternal illness, following a comprehensive evaluation by a physician confirming that the therapeutic benefits outweigh the potential risks, and under strict medical supervision with short-term and low-dose administration. If fever, pain, or other symptoms occur during pregnancy, prompt medical attention is necessary to determine a safer treatment plan under a physician's guidance.

In addition, pregnant women should also focus on dietary management, adequate rest, and regular prenatal checkups during pregnancy to ensure the health of both themselves and their fetuses.