How soon after infusion does an infusion reaction generally occur?

Generally, an infusion reaction refers to adverse reactions that occur during or after intravenous infusion. The onset time and symptoms of infusion reactions vary from person to person, but typically appear within 15 minutes to 1 hour after starting the infusion. Severe reactions may occur within 24 hours after infusion.

After infusion, symptoms such as chills, high fever, headache, nausea, and vomiting may occur. Individuals with mild reactions usually experience symptoms within 15 minutes to one hour; these symptoms often subside after discontinuing the medication. In severe cases, the infusion should be stopped immediately, and symptomatic treatment should be administered promptly. Delayed allergic reactions generally occur one day or more after the infusion. These reactions are usually mild and mostly manifest as rashes, commonly appearing on the chest, back, and other areas. The rash is typically evenly distributed with localized itching. Delayed allergic reactions generally do not require special attention and resolve spontaneously after stopping the drug. However, if symptoms are severe, antiallergic treatment may be necessary.

If an infusion reaction occurs, the infusion should be stopped immediately, and medical attention should be sought promptly. Before receiving an infusion, patients should inform their doctor of their allergy history and medication history so that the doctor can select appropriate drugs and dosages, thereby reducing the risk of infusion reactions.