Can azelaic acid and retinol be used together?
Azelaic acid and retinol generally should not be used together, as this may cause adverse reactions such as itching, stinging, and peeling.
Azelaic acid has strong penetrability and belongs to organic acid compounds. It can enhance the skin's absorption of nutrients and promote the shedding of older keratinized layers, resulting in a skin-brightening effect. Retinol accelerates skin metabolism and inhibits melanin production, providing certain anti-aging and skin-smoothing benefits. Moreover, retinol has an acidic pH. When both substances are applied simultaneously, they may irritate the skin; therefore, azelaic acid and retinol are typically not recommended for concurrent use.
Azelaic acid is a commonly used topical ointment, generally classified as a dermatological medication effective for treating mild to moderate inflammatory conditions and acne. Its use should usually be discussed with a doctor, and it should be applied according to medical instructions. Overuse or application on sensitive skin may lead to symptoms such as itching, stinging, and peeling. Patients who are allergic to the medication should generally avoid using it.
In addition, proper daily skincare should be maintained, and consumption of spicy or irritating foods should be minimized to prevent inflammation and acne outbreaks.