Why doesn't fever subside after taking anti-inflammatory medication, and what should be done?

Fever reduction, also known as antipyresis. If fever does not subside after taking anti-inflammatory medication, possible reasons may include insufficient duration ofmedication use, inappropriate drug selection for the condition, or severe illness. These issues can be improved through general treatments or changing medications. Specific analyses are as follows:

1. Insufficient duration of medication use

Due to individual differences in patients' physical conditions, the time required for a drug to take effect may vary. Generally, anti-inflammatory drugs begin to work approximately one to two hours after ingestion. If the patient has taken the medication for too short a period, the full therapeutic effect may not yet have manifested, resulting in persistent fever. In such cases, the patient may need to wait patiently.

2. Inappropriate drug for the condition

If fever is caused by a common cold, it is usually due to viral infection in the early stages. Anti-inflammatory drugs are generally ineffective against fevers induced by viral infections. Instead, symptomatic treatment should be administered, using appropriate medications such as Ganciclovir Capsules or Ibuprofen Sustained-Release Capsules.

3. Severe illness

It is also possible that the patient's fever is particularly severe, and a single type of anti-inflammatory drug may not be sufficient to reduce it. If an infection develops during the febrile period, combination therapy may be used under a doctor’s guidance, such as Azithromycin Capsules or Cefixime Capsules, to alleviate internal infection before continuing with anti-inflammatory treatment.

Besides the above reasons, persistent fever might also be related to insufficient drug dosage, inadequate fluid intake, pneumonia, or other causes. For an accurate diagnosis, patients are advised to visit a hospital for a thorough examination to identify the underlying cause and receive targeted treatment.