Is soapberry (Sapindus) toxic?

Generally speaking, Sapindus has certain toxicity. Sapindus is the seed of the plant Sapindus mukorossi from the Sapindaceae family and possesses mild toxicity, so it should not be used indiscriminately. The detailed analysis is as follows:

Sapindus is a traditional Chinese medicinal herb known for its effects of clearing heat, reducing swelling and relieving pain, as well as killing parasites and eliminating food accumulation. It is primarily used to treat conditions such as lung-heat-induced cough and wheezing, sore throat and throat obstruction, abdominal pain caused by roundworms, tinea infections, and trichomonal vaginitis. It can alleviate symptoms including itching, swelling, pain, and coughing in patients. Additionally, it helps clear heat and detoxify, resolve phlegm, relieve cough, eliminate food stagnation, and kill parasites. It is effective for treating excessive cough with thick sputum, and can also help relieve symptoms of stomach fullness, indigestion, and poor appetite.

Sapindus must be used under the guidance of a physician. Self-medication may lead to serious adverse reactions. During treatment, patients should avoid consuming spicy or irritating foods, as these may affect the drug's efficacy. Sapindus is typically taken internally as a decoction or ground into powder for oral use. However, due to its inherent toxicity, long-term or excessive use is not recommended. Moreover, pregnant women, individuals with impaired liver or kidney function, and those with spleen-stomach deficiency and cold should avoid using it.

Patients should only take this herb under medical supervision and must not self-administer. If any physical discomfort occurs, they should seek immediate medical attention at a hospital.