Reference range for normal values of 75g glucose screening

Oct 17, 2023 Source: Cainiu Health
Dr. Zhang Renling
Introduction
Under normal circumstances, the 75g glucose screening refers to the 75g oral glucose tolerance test (OGTT). The normal reference ranges are: fasting blood glucose ≤5.6 mmol/L, 1-hour post-glucose load blood glucose ≤10.3 mmol/L, 2-hour blood glucose ≤8.6 mmol/L, and 3-hour blood glucose ≤6.7 mmol/L.

Generally, the 75g glucose screening refers to the 75g oral glucose tolerance test (OGTT). The normal reference ranges are as follows: fasting blood glucose ≤5.6 mmol/L, 1-hour post-glucose load blood glucose ≤10.3 mmol/L, 2-hour blood glucose ≤8.6 mmol/L, and 3-hour blood glucose ≤6.7 mmol/L. A detailed explanation is as follows:

The 75g oral glucose tolerance test is a glucose-loading test primarily used to evaluate pancreatic β-cell function and the body's ability to regulate blood glucose levels. It is mainly employed as a confirmatory diagnostic test for gestational diabetes mellitus (GDM). Typically, the patient ingests 75 grams of anhydrous glucose dissolved in 250–300 mL of water. Blood samples are collected before ingestion and at 1, 2, and 3 hours afterward to measure blood glucose levels. If two or more readings meet or exceed the normal thresholds, gestational diabetes is diagnosed. If only one reading exceeds the normal value, impaired glucose tolerance is diagnosed.

Adequate preparation is essential before undergoing the 75g glucose tolerance test. For three days prior to the test, the individual should consume at least 150 grams of carbohydrates per day and maintain normal physical activity. Additionally, severe infections or trauma should be avoided, as they may cause stress-induced elevations in blood glucose levels.