Can glomerular filtration rate below 60 mL/min be restored?

Generally, whether a glomerular filtration rate (GFR) below 60 mL/min can be restored depends on the severity of the kidney disease. If the patient's kidney condition is mild, kidney function usually returns to normal after treatment. However, if the kidney disease is severe, it becomes significantly more difficult to restore normal function even with treatment.

The normal GFR range for adults and children over two years of age is 90–120 mL/min. In conditions such as acute kidney injury or chronic kidney failure, when the disease is mild, the decline in GFR is often reversible. With timely diagnosis and treatment, GFR levels can gradually return to the normal range.

If the underlying kidney disease is severe and not promptly treated after diagnosis, the GFR may progressively decline as the condition worsens, eventually leading to uremia. In such cases, a GFR below 60 mL/min is unlikely to return to normal.

It is recommended to control intake of protein, salt, and sugar, avoid diets high in salt, fat, and sugar, and engage in moderate physical activity regularly.