How is bile reflux gastritis treated?

Patients with bile reflux gastritis typically present with symptoms such as abdominal pain or distension, a bitter taste in the mouth, and acid regurgitation. During gastroscopy, bile staining may be observed adhering to the gastric body or fundus.

Bile reflux causes damage to the gastric mucosa, as harmful components in bile directly erode the mucosa and weaken its protective barrier, leading to clinical manifestations of gastritis or gastric ulcers.

For these patients, initial management should focus on enhanced acid suppression therapy alongside mucosal protection. Given the concurrent presence of bile reflux esophagitis, prokinetic therapy to improve gastrointestinal motility is also essential. Medications such as mosapride citrate or itopride may be used.