What medications are used for ovulation induction?

For a woman to conceive successfully, she must ovulate healthy oocytes. Some women experience infertility due to ovulatory disorders—failure to ovulate normally directly impairs fertility. When ovulation is impaired, ovulation-inducing medications can be used to achieve this goal. So, what are the available ovulation-inducing drugs? Let’s take a closer look below.

What Are the Common Ovulation-Inducing Drugs?

1. Human Menopausal Gonadotropin (HMG)

The first-line medication for inducing ovulation, indicated for anovulation of various etiologies except hyperprolactinemia-related infertility.

2. Luteinizing Hormone-Releasing Hormone (LHRH)

Indicated for anovulation caused by hypothalamic insufficiency. To mimic the natural pulsatile release of gonadotropin-releasing hormone (GnRH) in vivo, administration requires intravenous pulsatile infusion—a costly and inconvenient method, thus rarely used.

3. Bromocriptine

Indicated for anovulation associated with hyperprolactinemia.

4. Human Chorionic Gonadotropin (hCG)

hCG exerts luteinizing hormone (LH)-like activity; when administered as follicles approach maturity, it triggers ovulation.

5. Progynova (Estradiol Valerate)

Indicated for menopausal symptoms following natural or surgical menopause (e.g., post-oophorectomy) or non-cancerous conditions requiring ovarian suppression (e.g., radiation-induced ovarian failure), including hot flashes, night sweats, sleep disturbances, mood depression, irritability, headache, and dizziness.

Above is an overview of common ovulation-inducing medications. We hope this information is helpful to you.