What deficiency causes night blindness?

Apr 25, 2022 Source: Cainiu Health
Dr. Chen You
Introduction
A small number of patients with night blindness develop the condition due to vitamin A deficiency; however, most cases are not caused by nutritional deficiencies but rather by genetic mutations or inherited disorders. Conventional supplementation with medications or vitamins is ineffective for hereditary night blindness. Vitamin A deficiency was historically more common among malnourished children or populations in pre-modern societies; affected individuals may benefit from dietary sources rich in vitamin A, such as lamb liver and carrots.

Night blindness (nyctalopia) is an eye disorder typically characterized by impaired vision—such as blurred or unclear vision—in low-light conditions, including nighttime, dusk, or dimly lit environments. This condition is termed “night blindness.” So, what deficiency causes night blindness?

What Is Deficient in Night Blindness?

A small proportion of night blindness cases result from vitamin A deficiency; however, most cases are not nutritionally related but instead stem from genetic mutations or inherited disorders. Conventional supplementation with medications or vitamins is ineffective for hereditary night blindness. Vitamin A deficiency was historically more common among malnourished children or populations in pre-modern societies. Affected individuals may benefit from consuming vitamin A–rich foods such as lamb liver and carrots. β-carotene, found in many plant-based foods, can be converted into vitamin A in the body and thereby supports improved night vision.

If night blindness arises from nutritional deficiency, increasing intake of lutein-rich foods—such as carrots and corn—may help improve symptoms. Conversely, if night blindness is caused by a genetic disorder, neither the aforementioned foods nor supplements offer any therapeutic benefit. Currently, gene therapy represents the only potentially effective treatment option; however, it is indicated only for select patients, and not all individuals with night blindness are eligible.

Symptoms are typically most pronounced under low-light conditions, such as at night. If you experience any of the above-mentioned symptoms of night blindness, prompt medical evaluation is recommended. We hope this information has been helpful. Wishing you good health and happiness!