What is the normal value of human chorionic gonadotropin (hCG)?

Nowadays, many pregnant women undergo regular health check-ups to promptly confirm whether they are pregnant. Human chorionic gonadotropin (hCG) is a hormone produced during pregnancy, and its concentration is used to determine pregnancy status. So, what constitutes the normal hCG level?

What Is the Normal hCG Level?

The normal hCG level is generally less than 75 U/mL; levels exceeding 150 U/mL may indicate pregnancy. However, reference ranges vary significantly among hospitals due to differences in assay reagents used. Therefore, local hospital reference values should be considered definitive. Levels above the reference range suggest possible pregnancy, whereas values within the reference range indicate a negative result.

Human chorionic gonadotropin (hCG) is a glycoprotein secreted by the syncytiotrophoblast cells of the placenta. Following fertilization, the zygote migrates into the uterine cavity and implants. During embryonic development, the placental syncytiotrophoblast secretes large amounts of hCG, which enters maternal circulation and is subsequently excreted in urine. Serum and urinary hCG concentrations rise rapidly during weeks 1–2.5 of gestation. Peak hCG levels occur around week 8 of pregnancy, followed by a gradual decline to moderate levels by approximately month 4, remaining stable until term.

Note that certain non-pregnancy-related conditions—including pancreatic cancer, lung cancer, and colorectal cancer—may also cause elevated hCG levels. A definitive diagnosis therefore requires comprehensive evaluation, incorporating menopausal history, ultrasound imaging, and other relevant clinical data. We hope this information has been helpful! Wishing you good health and happiness!