What should I do if I have an allergic reaction to bed bug bites?

Allergic reactions to bed bug bites can be treated with either topical or oral medications. Topical treatments commonly include cooling oil and calamine lotion, which effectively relieve localized itching. If the resulting rash covers a large area, oral medications such as loratadine or vitamin C may be considered—both demonstrate good therapeutic efficacy—but must be taken only under a physician’s guidance.