What should I do about nail separation?

Nail separation requires proper local care. If caused by a fungal infection, topical antifungal medications may be applied under a physician’s guidance. If resulting from trauma (e.g., impact), local disinfection and wound care are essential to prevent secondary infection. Fungal infection of the nail can lead to onycholysis (separation of the nail plate from the nail bed), nail thickening, and nail atrophy; treatment typically involves topical antifungal agents such as miconazole nitrate cream, terbinafine hydrochloride cream, or ketoconazole cream.