What medications are effective for treating ankylosing spondylitis?

Ankylosing spondylitis is a chronic inflammatory disease that primarily affects the joints in the spine and pelvis. Medications effective for treating ankylosing spondylitis include nonsteroidal anti-inflammatory drugs (NSAIDs), slow-acting drugs, glucocorticoids, and biologic agents. 1. Nonsteroidal anti-inflammatory drugs such as ibuprofen and loxoprofen can relieve symptoms and improve morning stiffness and muscle spasms. 2. Slow-acting drugs such as methotrexate, sulfasalazine, and tripterygium wilfordii can help control disease activity. 3. Glucocorticoids are generally not used as routine treatment, but may be administered in low doses for short periods under specific circumstances. 4. Biologic agents, such as tumor necrosis factor (TNF) inhibitors, are effective options for controlling the disease, although they are expensive. Patients should strictly follow their doctor's instructions regarding medication and monitor for possible side effects. If new symptoms appear or pain worsens, prompt medical attention is advised.