What conditions does tacrolimus ointment treat?
Jun 22, 2020
Source: Cainiu Health
Dr. Liu Wan
Introduction
What is tacrolimus ointment used for? Tacrolimus ointment is indicated for the treatment of moderate to severe atopic dermatitis. It is intended for short-term or intermittent long-term use in patients with atopic dermatitis who are at potential risk from conventional therapies, who have had an inadequate response to conventional therapies, or who are intolerant to conventional therapies. Atopic dermatitis is also known as atopic eczema. The exact cause of atopic dermatitis remains unknown.
Tacrolimus ointment is a non-steroidal topical anti-inflammatory agent with additional antipruritic (itch-relieving) properties. Atopic dermatitis is a relatively burdensome skin disorder. Children and adolescents are at high risk for developing this condition; once affected, patients experience severe pruritus (itching) and often develop eczematous skin lesions. Tacrolimus ointment may be used to help manage these symptoms.
What conditions does tacrolimus ointment treat?
Tacrolimus ointment is indicated for the treatment of moderate-to-severe atopic dermatitis. It is suitable for short-term or intermittent long-term therapy in patients for whom conventional therapies pose potential risks, who respond inadequately to conventional treatments, or who are intolerant to conventional therapies. Atopic dermatitis—also known as atopic eczema—is a multifactorial disorder whose exact etiology remains unclear. Contributing factors include genetic predisposition, food allergens, inhalant allergens, autoantigens, infections, and impaired skin barrier function. General management strategies involve identifying and eliminating potential triggers, along with symptomatic treatment. As an immunosuppressant, tacrolimus ointment exerts localized immunomodulatory effects. Dosage differs between adults and children.
Additional Information: Important Safety Considerations for Tacrolimus Ointment
1. Tacrolimus ointment is contraindicated in immunocompromised adults and children.
2. It is contraindicated in patients with a known hypersensitivity to tacrolimus or any other component of the formulation.
3. If signs and symptoms of atopic dermatitis do not improve within six weeks, patients should be re-evaluated by a healthcare provider to confirm the diagnosis.
The above outlines the primary indication for tacrolimus ointment—namely, the treatment of moderate-to-severe atopic dermatitis. During treatment with tacrolimus ointment, avoid concurrent phototherapy (e.g., UV light therapy), exposure to fluorescent lamps, sunbeds, or direct sunlight. We hope this information is helpful—and wish you good health and happiness!
