What is the normal value of hCG?

Human chorionic gonadotropin (hCG) is a hormone produced by the placenta after implantation. Typically, fertilization occurs approximately one week prior to implantation into the uterine cavity, after which hCG secretion begins.

What is the normal hCG level?

The hCG level—also known as the human chorionic gonadotropin level—normally ranges from 0 to 5 mIU/mL in non-pregnant individuals. hCG is a glycoprotein secreted by trophoblastic cells of the placenta and consists of an α- and a β-subunit dimeric glycoprotein. Measurement of hCG is clinically significant for early pregnancy detection and plays an important role in the differential diagnosis and monitoring of pregnancy-related disorders, trophoblastic diseases, and certain malignancies.

Clinically, hCG testing is primarily used to assess pregnancy-related conditions and to evaluate disease progression and prognosis in associated clinical disorders. These include early pregnancy, hydatidiform mole, invasive mole, choriocarcinoma (also termed gestational trophoblastic neoplasia), seminoma, teratoma, gastric cancer, pancreatic cancer, lung cancer, colorectal cancer, hepatocellular carcinoma, ovarian cancer, threatened abortion, and spontaneous abortion—all of which are closely linked to hCG measurement.

Serum hCG testing is commonly employed in the clinical diagnosis of ectopic pregnancy. Typically, ultrasound examination is performed at 6–7 weeks’ gestation. If no intrauterine gestational sac is identified on ultrasound, serum hCG levels are measured. An ectopic pregnancy is suspected when serum hCG exceeds 2,500–3,000 U/L in the absence of an intrauterine gestational sac. We hope this information is helpful to you!