What causes a persistent feeling of nausea?

Aug 24, 2022 Source: Cainiu Health
Dr. Zhao Haiming
Introduction
There are many causes of nausea. Liver function tests should be performed to check for elevated transaminase levels. Elevated transaminases are commonly associated with hepatobiliary disorders, such as chronic hepatitis B, chronic hepatitis C, fatty liver disease, drug-induced hepatitis, alcoholic hepatitis, or gallbladder diseases—including chronic cholecystitis, gallbladder polyps, and gallstones—all of which may cause nausea. Therefore, liver function testing should be the first step when evaluating a patient presenting with nausea.

Some patients frequently experience nausea and vomiting. Persistent nausea and vomiting can lead to a decline in overall health and even increase the risk of developing certain chronic conditions. Therefore, when patients present with nausea and vomiting, diagnostic tests should be performed to identify the underlying cause. But what exactly causes persistent nausea?

What Causes Persistent Nausea?

Nausea has many potential causes. Liver function tests should be conducted to assess whether transaminase levels are elevated. Elevated transaminases are commonly associated with hepatobiliary disorders—such as chronic hepatitis B or C, fatty liver disease, drug-induced hepatitis, alcoholic hepatitis—or gallbladder conditions—including chronic cholecystitis, gallbladder polyps, and gallstones—all of which may trigger nausea. Thus, liver function testing should be among the first diagnostic steps when a patient presents with nausea. Gastrointestinal disorders—particularly gastritis—may also cause nausea, often accompanied by symptoms such as acid reflux, belching, and epigastric pain, which are hallmark features of gastritis.

For women of childbearing age, delayed menstruation coupled with recurrent nausea strongly suggests pregnancy; early pregnancy testing is therefore recommended. Additionally, persistent nausea may stem from physiological or psychological factors—including excessive anxiety, chronic stress, or prolonged depression. Patients with gastrointestinal diseases such as gastritis or gastric ulcers may also experience nausea and vomiting. In such cases, individuals should seek medical evaluation for appropriate diagnostic testing and treatment—including medications to improve gastrointestinal motility.

Patients are advised to avoid spicy and irritating foods and instead consume bland, easily digestible meals. Establishing healthy lifestyle habits is also essential. We hope this information proves helpful.