What are the contraindications of glucocorticoids?
Sep 07, 2022
Source: Cainiu Health
Dr. Pan Yongyuan
Introduction
Contraindications for glucocorticoids typically include cautious use in patients with hypersensitivity, avoidance of high-dose administration, and cautious use in patients with tuberculosis or viral infections. Patients with heightened sensitivity should use glucocorticoids with caution to prevent allergic reactions. High-dose administration should be avoided to prevent complications such as diabetes mellitus or secondary infections. Glucocorticoids should be used cautiously in patients with tuberculosis or viral infections, as they may elevate blood pressure and increase the risk of cerebrovascular accidents.
Contraindications for glucocorticoids generally include cautious use in individuals with hypersensitive constitutions, avoidance of high-dose administration, and caution in cases of tuberculosis or viral infections.
1. Use with caution in individuals with hypersensitive constitutions
In clinical practice, commonly used glucocorticoid medications primarily include prednisone. Patients with particularly sensitive constitutions should use these drugs cautiously. Individuals who are allergic to prednisone or other adrenocorticosteroid medications must avoid using such drugs to prevent allergic reactions.
2. Avoid high-dose use
Glucocorticoids should typically be used according to standard dosage instructions under a physician's guidance. High-dose use may easily lead to gastrointestinal ulcers, diabetes, and other conditions, and could also result in secondary infections and other adverse effects.
3. Use with caution in tuberculosis and viral infections
Patients suffering from tuberculosis or viral infections should use glucocorticoids cautiously to avoid elevated blood pressure and potential cerebrovascular accidents. If the drug must be used, appropriate anti-infective treatment should be administered under medical supervision. When long-term glucocorticoid therapy is discontinued, the dosage should be gradually reduced under medical guidance; abrupt discontinuation should be avoided.
