What is the incidence rate of trisomy 21 syndrome?
Oct 12, 2022
Source: Cainiu Health
Dr. Xie Zixing
Introduction
The incidence rate of trisomy 21 syndrome is approximately 0.5% to 0.6%. Trisomy 21 syndrome usually refers to a condition caused by chromosomal abnormalities during embryonic development. Under normal circumstances, human cells contain 23 pairs of chromosomes; however, in trisomy 21 syndrome, there is an extra chromosome in the 21st pair, a condition clinically known as Down syndrome.
The incidence rate of trisomy 21 syndrome is approximately 0.5% to 0.6%.
Trisomy 21 syndrome typically refers to a condition caused by chromosomal abnormalities during embryonic development. Normally, human cells contain 23 pairs of chromosomes. Trisomy 21 syndrome occurs when there is an extra chromosome in the 21st pair and is clinically known as Down syndrome. Children with Down syndrome may exhibit developmental delays, intellectual disability, distinctive facial features, and multiple congenital malformations. Currently, there is no complete cure for this condition. However, the incidence rate of trisomy 21 syndrome is relatively low, around 0.5% to 0.6%.
During pregnancy, further screening for trisomy 21 syndrome is possible. Generally, between weeks 11 and 13 of pregnancy, an NT (nuchal translucency) scan can be used to assess fetal development. Around weeks 16 to 18, maternal blood tests (Down syndrome screening) can be performed. If necessary, non-invasive DNA testing or amniocentesis during pregnancy can further confirm whether the fetus has trisomy 21 syndrome.
