How is a skin biopsy performed?
Skin biopsy is an invasive clinical procedure involving the collection of tissue samples from localized skin lesions for histopathological examination, aiming to achieve a definitive clinical diagnosis or guide treatment. The specific steps are as follows:
1. Disinfection: Routinely disinfect the local surgical site.

2. Anesthesia: Local infiltration anesthesia is commonly used. The anesthetic should be injected around the lesion, not directly into the skin lesion itself.
3. Sampling: Make an incision using a scalpel, keeping the blade perpendicular to the skin surface. The incision should follow the natural skin lines and extend deep into the subcutaneous tissue. The specimen should typically measure approximately 0.2 cm in width and 1 cm in length. After removal, suture the wound.
4. Specimen submission: Verify the patient's information, confirm accuracy, and then send the specimen to the laboratory for pathological examination.