Does taking antibiotics affect a routine blood test?

Nov 20, 2022 Source: Cainiu Health

Dr. Yang Shuwen

Introduction

Taking antibiotics usually affects complete blood count (CBC) tests. Some antibiotics, such as penicillin, cephalosporins, or macrolides, may cause leukopenia (reduced white blood cell count) when used long-term, as their mechanism involves killing bacteria causing infections. CBC results may show false negatives, such as decreased white blood cells or anemia. It is recommended that patients take antibiotic medications only under the guidance of a physician.

Generally, taking antibiotics can affect routine blood tests.

Long-term use of antibiotic medications may lead to reduced white blood cell counts, as these drugs work by killing bacterial infections. This could result in false-negative results in blood tests, such as decreased white blood cells or anemia. Since antibiotics are potent medications with varying effects on the body, it's essential to fast and avoid taking other medications during blood testing to ensure accuracy. Patients scheduled for a routine blood test should ideally avoid taking antibiotics during this period. If antibiotics have been taken, it's recommended to wait at least one week after stopping the medication before undergoing a routine blood test at the hospital.

Patients are advised to take antibiotics only under a doctor's supervision. Overuse or prolonged use should be avoided to prevent the development of drug resistance, weakened immunity, and adverse effects such as gastric ulcers and erosive gastritis.

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