Why does bleeding occur after receiving heparin?
Heparin is a common anticoagulant that can delay or inhibit blood coagulation in vivo or in vitro. Persistent bleeding after receiving heparin injection may be caused by coagulation disorders, improper medication use, incorrect compression techniques, or other reasons.
1. Coagulation Disorders
These are generally caused by genetic or acquired factors. After procedures such as tooth extraction, minor surgeries, or injections, prolonged bleeding often occurs; therefore, bleeding may also persist after heparin injection. Common treatments include supplementing clotting factors, using fresh plasma or desmopressin acetate injection. Additionally, applying ice packs and bandage pressure can help stop bleeding until it completely resolves.
2. Improper Medication Use
Heparin delays blood coagulation. If too much is administered, spontaneous bleeding may occur, leading to persistent bleeding at the injection site. Early signs of overdose include mucosal damage and bleeding from wounds or injection sites, while severe cases may result in internal hemorrhage. However, since heparin is rapidly metabolized, mild overdoses can be resolved simply by discontinuing the drug. In cases of severe symptoms, intravenous administration of protamine sulfate injection can neutralize heparin's effects and alleviate bleeding at the injection site.
3. Incorrect Compression Technique
Persistent bleeding at the injection site after heparin administration may also result from inadequate compression. After receiving heparin, the injection site should be compressed for 15 to 20 minutes. It is important to press with the thumb so that the skin is depressed approximately 1 cm, avoiding rubbing or applying heat to the injection site.
In addition, pregnant patients may experience bleeding due to placental-related factors.