Can taking amlodipine besylate tablets cause toothache?
Taking amlodipine besylate tablets may cause toothache.
Amlodipine besylate belongs to the class of calcium channel blockers and is clinically used for treating essential hypertension, as well as chronic stable angina and variant angina. The antihypertensive mechanism of this drug involves directly relaxing vascular smooth muscle. It also dilates peripheral small arteries and coronary arteries, reducing total vascular resistance and relieving coronary artery spasm, thereby decreasing cardiac afterload and alleviating angina. After taking amlodipine besylate tablets, the drug may directly affect fibroblasts in the gums, causing cell proliferation and resulting in pain. This is considered one of the drug's side effects; therefore, toothache may occur with the use of amlodipine besylate tablets.
Additionally, taking amlodipine besylate tablets may lead to other side effects such as nausea, abdominal pain, palpitations, dizziness, frequent urination, and joint pain. Therefore, patients should use this medication only under the guidance of a physician to help minimize the impact of potential side effects on the body.