Can EB virus cause cancer?

Jan 04, 2023 Source: Cainiu Health
Dr. Qi Zhirong
Introduction
Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a DNA virus. EBV infection is often associated with nasopharyngeal carcinoma, lymphoma, and gastric cancer. However, being positive for EBV does not necessarily mean that cancer is present; rather, it acts as a contributing factor in the development of these cancers. Individuals who are EBV-positive should take preventive measures, and if experiencing any discomfort, are advised to seek medical evaluation promptly to rule out the possibility of malignant transformation.

Generally, Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a DNA virus. EBV infection is often associated with nasopharyngeal carcinoma, lymphoma, and gastric cancer. However, a positive EBV test does not necessarily mean the presence of cancer; rather, it is a significant contributing factor to these cancers. Individuals testing positive for EBV should focus on prevention and seek prompt medical evaluation if experiencing any symptoms to rule out malignant transformation.

In most people, the immune system can effectively control EBV, making it similar to common cold viruses without highly specific characteristics. EBV belongs to the herpesvirus family and primarily spreads through close contact. In adults, infection typically presents acutely with fever, pharyngitis, rash, and hepatosplenomegaly. Laboratory tests may show a marked increase in white blood cell count.

After infecting humans, both carriers and symptomatic patients serve as sources of transmission. The virus mainly spreads via saliva but can also transmit through blood. Therefore, personal protective measures are important to minimize the risk of EBV infection. In populations with nasopharyngeal carcinoma, EBV genetic material is commonly detected.

EBV infection can be treated with medications, which vary depending on individual patient conditions. Vaccination may also help prevent infection. Regular physical exercise and improving overall immunity are recommended. Individuals who are EBV-positive should pay particular attention to their risks of developing nasopharyngeal carcinoma, lymphoma, and gastric cancer.

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