Can adenomyoma of the uterus become cancerous?
Adenomyomas of the uterus generally do not have the potential to become cancerous.
Uterine adenomyoma is a manifestation of adenomyosis, primarily characterized by localized growth of endometrial tissue within the uterine muscle layer, forming a nodule or mass similar to an intramural uterine fibroid, known as adenomyoma. Adenomyomas lack a distinct capsule. The main clinical symptoms include increased menstrual bleeding, prolonged menstruation, and progressively worsening dysmenorrhea (painful periods), which commonly occur in parous women over 30 years of age. On physical examination, the uterus appears uniformly enlarged with localized nodular protrusions, feels firm in texture, and is tender to palpation—especially during menstruation. If the adenomyoma is small and associated with only mild or insignificant dysmenorrhea, no specific treatment is required; regular follow-up with ultrasound examinations is sufficient. However, if the adenomyoma is large and accompanied by severe, intolerable dysmenorrhea, surgical intervention is recommended to achieve a definitive cure.
Women are advised to undergo regular gynecological check-ups, manage emotional well-being in daily life, avoid excessive stress and overthinking, and prevent undue fatigue. Maintaining an optimistic mindset helps support hormonal balance.